- 5 New Playable Factions - Play through the new Warpath Campaign or in multiplayer as one of 5 new American Indian factions in Empire: Total War, including the Iroquois, Huron, Plains, Pueblo and Cherokee nations.
- Expanded North American Territories - A new, more detailed North American Campaign Map featuring new regions and a new start date.
- New Elite Units - Command new Elite units specific to each American Indian faction including Mohawk Elite Warriors, Cheyenne Dog Soldiers, Navajo Scout Warriors and many more.
- Shaman and Scout Agents - Two new agent types - Infiltrate enemy territory with the new Shaman unit and sabotage the opposition with the cunning Scout.
- New Tribal Technologies - 18 new tribal technologies including Spirit Medicine, the Call of the Wild and Dreamwalking creating a brand new tribal technology tree.
- New Objectives - New winning objectives for each of the playable factions.


